The General Lying-In Hospital was opened in April, 1767, as the Westminster New Lying-in Hospital, on the north side of Westminster
Bridge Road Lambeth with Dr. John Leake as its first physician. Early in the 1820s the governors decided to move to new premises.
They acquired a building lease of a plot of ground with 100 foot frontage at grid reference TQ308797 on the east side of York
Road, Lambeth. The new building was designed by Henry Harrison and cost about £3,000.